Welcome to the Gutmann Laboratory

Using neurofibromatosis type 1 (NF1) as a model system, the Gutmann laboratory aims to characterize the genomic, genetic, cellular and molecular factors that contribute to the development of nervous system tumors (gliomas and neurofibromas) and cognitive problems (learning and behavioral deficits). The goal of this work is to establish new treatments for people with NF, and to better understand related medical problems in the general population, including adult and childhood brain tumors, nerve tumors, sarcoma and autism.

Gutmann Awarded International Fellowships

David H. Gutmann, MD, PhD, has been awarded the Alexander von Humboldt Professorship, Germany’s highest academic award for researchers outside the country, and has been named an Einstein Visiting Fellow by the Berlin Institute of Health. Dr. Gutmann will be working with the Max Delbrück Center for Molecular Medicine, co-leading a team to investigate the relationship between a type of brain cell, known as microglia, and neurological diseases, including brain tumors and autism.
NF Center Trainee Publishes World’s Largest Study on Brainstem Tumors in Neurofibromatosis 1 (NF1)

Children with NF1 are at risk for developing brain tumors. While much is known about the more common optic pathway gliomas, comparatively less is known about NF1-associated brainstem gliomas. To learn more about these tumors, Dr. Jasia Mahdi and her colleagues worked with investigators at Lurie Children’s Hospital in Chicago, Children’s Hospital of Philadelphia, and Children’s National Medical Center in Washington DC.
Corina Anastasaki, PhD Promoted to Senior Research Scientist

Corina Anastasaki, PhD has recently been promoted to the role of Senior Research Scientist in the Gutmann laboratory. While she will remain active in fundamental laboratory research, she is also guiding the scientific direction of translational research in the Center, and has assumed public outreach responsibilities aiming to bring the NF Center to the public.
$3.5 Million Funds Study Aimed at Applying Precision Medicine to Rare Tumor Disorder

David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor and director of the Neurofibromatosis Center at Washington University School of Medicine in St. Louis, received a $3.5 million grant to study why people with the same genetic mutation develop markedly different signs and symptoms.
NF Center Researchers Identify a New Growth Regulatory Circuit Critical for Malignant Glioma Survival

Glioblastoma (GBM) are the most malignant brain tumor in adults, with over 13,000 people in the United States dying from these cancers each year. Read more about how Dr. Yuan Pan, and her colleagues at the Washington University NF Center, focused research on how tumor growth in this class of GBM is controlled.
Michelle Wegscheid, MD/PhD trainee, Joins the Gutmann Laboratory

The laboratory of Dr. David Gutmann at the Washington University Neurofibromatosis (NF) Center welcomes Michelle Wegscheid as an MD/PhD trainee in the Neurosciences Program at Washington University. With her experience and skill set, she hopes to advance our understanding of brain development in individuals with NF1.

Welcome to the Gutmann Laboratory

Gutmann Awarded International Fellowships

NF Center Trainee Publishes World’s Largest Study on Brainstem Tumors in Neurofibromatosis 1 (NF1)

Corina Anastasaki, PhD Promoted to Senior Research Scientist

$3.5 Million Funds Study Aimed at Applying Precision Medicine to Rare Tumor Disorder

NF Center Researchers Identify a New Growth Regulatory Circuit Critical for Malignant Glioma Survival

Michelle Wegscheid, MD/PhD trainee, Joins the Gutmann Laboratory