Researchers

Principal Investigator

PI

David H. Gutmann, MD, PhD, is the Donald O. Schnuck Family Professor, Vice Chair for Research Affairs in Neurology and Director of the Washington University NF Center

David H. Gutmann, MD, PhD

Dr. Gutmann received his MD and PhD degrees at the University of Michigan Medical School, working as a graduate student in immunogenetics under the guidance of Dr. John Niederhuber. He then received residency training in Neurology at the University of Pennsylvania, where he was mentored by Dr. Kenneth Fischbeck in neurogenetics, prior to joining the laboratory of Dr. Francis S. Collins to identify the function of the NF1 gene.

For over 20 years, Dr. Gutmann has cared for children and adults with neurofibromatosis, as well as directed a basic research laboratory focused on using NF as a genetic model system to better understand normal brain and brain tumor development relevant to improving the lives of people with NF and related disorders. His work has been internationally recognized, with numerous honors, including the 2012 Children’s Tumor Foundation Frederich von Recklinghausen and an R35 Research Program Award from the National Institutes of Health.Gutmann CV

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View David H. Gutmann’s Curriculum Vitae »
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Staff Scientists

Corina Anastasaki, PhD

Education:
BS, Genetics, University of York, 2006
PhD in Human Genetics, University of Edinburgh, 2011
Research Focus:
Discovering new approaches (utilizing iPSCs) to identify targets for managing NF1 neuronal dysfunction.

View Dr. Anastasaki’s publications

Jason Papke, MS 

Education:
MS, St. Louis University
Research Focus:
Stem cell modeling of human neurologic diseases.

 

Shilpa Sanapala, MS

Education:
BS, Biotechnology, Jawaharlal Nehru Technological University, India (2007)
MS, Biotechnology, University of Texas at San Antonio, Texas (2011)
Research Focus:
Assisting with the maintenance of Gutmann Research Laboratory mouse colony and the study of T-cell-microglia interactions for Nf1 optic glioma growth.

Postdoctoral Fellows

Nicole Brossier, MD, PhD

Education:
MD, PhD, University of Alabama, Birmingham
Research Focus:
Defining the cells of origin for pediatric
low-grade brain tumors (gliomas).

Kristen Jacobsen, PhD

Education:
PhD, University of Colorado, Denver
Research Focus:
Defining the molecular and cellular basis for sexually-dimorphic brain phenotypes in NF1

 

Graduate Trainees

Xiaofan (Gary) Guo, MD

Education:
MD, School of Medicine, Shandong University, China
Research Focus:
Leveraging low-grade glioma stem cells to identify new treatments for pediatric brain tumors.

Michelle Wegscheid, BS

Education:
BS, Biochemistry, University of Illinois Urbana-Champaign, 2013
MD, PhD candidate, Washington University in St. Louis, 2014 – present
Research Focus:
Engineering cerebral organoids from NF1 patient stem cells to investigate disease specific neurodevelopmental anomalies and tumorigenesis.

 

 

Undergraduate Trainees

Kyung Park

Education:
Pursuing undergraduate degree, Washington University in St. Louis
Research Focus:
Working with Dr. Corina Anastasaki to investigate sexually dimorphic sleep disturbances in mouse models of NF1.

Kelly Hartigan

Education: 
Pursuing undergraduate degree, Washington University in St. Louis
Research Focus:
Working with Michelle Wegscheid on modeling neurodevelopment and low-grade gliomas using cerebral organoids derived from NF1 patient stem cells.

 

Alumni

Anthony J. Apicelli, MD, PhD

Assistant Professor
Department of Radiation Oncology
Washington University
NIH F32 NRSA Awardee

M. Livia Bajenaru, PhD

Research Assistant Professor
Bascom Palmer Eye Institute
University of Miami
NIH F32 NRSA Awardee

Hugh Bender, PhD

Post-Doctoral Research Fellow
University of California, Irvine
CTF Young Investigator Awardee

Ran Chen, PhD

Post-Doctoral Research Fellow
Department of Pediatrics, Hematology and Oncology
Washington University

Yi-Hsien Chen, PhD

Staff Scientist
Genome Engineering and iPSC Center
Washington University
ABTA Post-Doctoral Fellowship Awardee

Patrick J. Cimino, MD, PhD

Assistant Professor
Pathology
University of Washington

Lucy D’Agostino McGowan, MS

Graduate Student
Vanderbilt University

Sonika Dahiya, MD

Assistant Professsor
Department of Pathology
Washington University

Biplab Dasgupta, PhD

Associate Professor
Department of Pediatrics
University of Cincinnati

Kelly Diggs-Andrews, PhD

Education Fellow
American Society for Microbiology
NCI Diversity Grant Awardee

Kevin C. Ess, MD, PhD

Associate Professor
Director, Division of Pediatric Neurology
Vanderbilt University

Morgan Freret, MD, PhD

Resident in Radiation Oncology

Mark Gerber, PhD

Principal R&D Scientist and Supervisor
Cell Design Studio at Millipore-Sigma
Washington University
NIH F32 NRSA Awardee

Balazs Hegedus, PhD

Principal Investigator
Medical University of Vienna

Angela Hirbe, MD, PhD

Assistant Professor of Medicine
Medical Oncology
Washington University

Sean Houshmandi, PhD

Principal R&D Scientist and Supervisor
Key Account and Business Development Manager
A Qiagen/BD Company
NIH F32 NRSA Awardee

Ibrahim Hussain, MD

Resident
Neurosurgery
Memorial Sloan Kettering Cancer Center
Doris Duke Medical Fellow

Da Yong Lee, PhD

Senior Researcher
Korea Institute of Bioscience and Biotechnology
CTF Young Investigator Awardee

Stephanie Morris, MD

Co-Director
NF Clinical Program
St. Louis Children’s Hospital
Assistant Professor
Division of Pediatric Neurology
Washington University

Yuan Pan, PhD

Post-Doctoral Research Fellow
Stanford University
Michelle Monje-Deisseroth, MD, PhD Lab: NF1 collaborative project

Winnie Pong, PhD

Medical Writer
EBSCO Information Services
Orion Bionetworks
Keck Fellowship Awardee

Danielle Sandsmark, MD, PhD

Assistant Professor
Department of Neurology
University of Pennsylvania

Mukesh Sharma, PhD

Biomedical Informatics Project Manager
Center for Biomedical Informatics
Washington University

Anne Solga, PhD

Post-Doctoral Research Fellow
Washington University

Ezequiel I. Surace, PhD

CONICET Investigator
Instructor
Department of Physiology, Molecular and Cellular Biology
University of Buenos Aires

Eric Uhlmann, MD, PhD

Instructor
Department of Neurology
Beth Israel Deaconess Medical Center
NIH F32 NRSA Awardee

Min Xiong, MD, PhD

Attending Physician
Reproductive Medicine Center
Tongji Hospital, CHINA

Tu-Hsueh Yeh, MD, PhD

Associate Professsor
Chief, Division of Movement Disorders
Department of Neurology
Chang Gung University